VHL disease is a rare genetic condition in which cysts and tumors unpredictably grow throughout the body. Understanding VHL disease-related tumors and how they occur can help you make treatment decisions with your doctor.
Merck is committed to helping make treatment available to those who need it. Learn about your options for getting your prescribed WELIREG medication.
Find helpful information about VHL disease-related tumors and how WELIREG may help. Plus, get tips for managing treatment along the way.
WELIREG is a prescription medicine used to treat adults with von Hippel-Lindau (VHL) disease who need treatment for a type of kidney cancer called renal cell carcinoma (RCC), tumors in the brain and spinal cord called central nervous system hemangioblastomas, or a type of pancreatic cancer called pancreatic neuroendocrine tumors, that do not need surgery right away.
It is not known if WELIREG is safe and effective for use in children.
WELIREG may cause serious side effects. WELIREG may cause harm to your unborn baby.
WELIREG may cause serious side effects, including:
Low red blood cell counts (anemia). Low red blood cell counts are common with WELIREG and can be severe. You may need a blood transfusion if your red blood cell counts drop too low. Your health care provider will do blood tests to check your red blood cell counts before you start and during treatment with WELIREG. Tell your health care provider if you get any symptoms of low red blood cell counts, including tiredness, feeling cold, shortness of breath, chest pain, or fast heartbeat.
Low oxygen levels in your body. WELIREG can cause low oxygen levels in your body that can be severe and may require you to stop treatment with WELIREG, receive oxygen therapy, or be hospitalized. Your health care provider will monitor your oxygen levels before you start and during treatment with WELIREG. Tell your health care provider or get medical help right away if you get symptoms of low oxygen in your body, including shortness of breath or increased heart rate.
Harm to your unborn baby. Treatment with WELIREG during pregnancy can cause harm to your unborn baby.
Females who are able to become pregnant:
Males with female partners who are able to become pregnant:
Before taking WELIREG, tell your health care provider about all of your medical conditions, including if you:
Tell your health care provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. WELIREG and certain other medicines can affect each other and cause serious side effects.
The most common side effects of WELIREG include:
WELIREG may cause fertility problems in males and females, which may affect your ability to have children. Talk to your health care provider if this is a concern for you.
These are not all the possible side effects of WELIREG. Call your health care provider for medical advice about side effects.
Please read the Medication Guide for WELIREG, including additional important information on the above warning about harm to an unborn baby, and discuss it with your doctor. The physician Prescribing Information also is available.